Opportunistic screening, upgraded

Turn routine CT scans into fracture prevention.

Phantomless, multi-domain biomarkers from existing imaging. A clinical-grade signal in under a minute, without disrupting workflow.

Phantomless calibrationMulti-domain biomarkersWorks with existing CTs
73M1
CT scans annually (US)
<60s2
Processing per scan
+113%3
More patients identified
Bone Health Index
Example output (mock)
PACS-ready
Example bone health risk output
OverlayRisk stratificationReport PDF

The point is not another number. It is a workflow-compatible risk signal that shows up when the patient is already in the system.

73 million missed opportunities

The signal is already in the CT. The system just does not collect it.

Every year, CT scans are performed for reasons unrelated to bone health. Meanwhile, a large share of patients who suffer fractures never receive a diagnosis beforehand.

These scans contain bone, muscle, and fat biomarkers that correlate with fragility risk, but that data goes unused.

The cost? Avoidable fractures, avoidable spend, and avoidable loss of independence.

Data exists

CT scans already contain the relevant biomarkers.

Data unused

Traditional workflows cannot extract it at scale.

Patients at risk

Warning signs go undetected until the fracture.

Built for operators, designed for outcomes

Different stakeholders care about different things. Here is what changes for each one.

Radiology groups
Workflow-first adoption
  • • Add preventive value without changing protocols
  • • PACS/API-ready outputs and structured reporting
  • • A path to new revenue streams and differentiated service
Health systems
Care gap closure
  • • Identify silent risk before the fracture event
  • • Automate stratification and care coordination triggers
  • • Align with value-based goals and population health
Investors and accelerators
Execution and defensibility
  • • Clear wedge: opportunistic CTs at massive scale
  • • Moat: calibration + multi-domain biomarkers + workflow
  • • Validation plan and regulatory pathway defined

Seeing the complete picture

Phantomless calibration plus multi-domain biomarkers enables opportunistic screening that actually scales.

We do not just measure bone density.

We measure fracture risk.

Phantomless calibration

Standardizes measurements across scanners without external calibration equipment.

Multi-domain analysis

Bone density, muscle quality, and fat distribution combined into a risk signal.

Universal compatibility

Designed for real-world CT variation, without workflow disruption.

How it works

Six steps. Zero workflow disruption.

Clinical impact that scales

BHI creates value for patients and healthcare systems simultaneously—earlier detection, no workflow disruption, and measurable cost avoidance.

For patients

  • Early detection before fractures occur—catching decline when intervention is most effective
  • Longitudinal tracking monitors bone health changes over time using routine imaging
  • Zero additional burden—no extra appointments, no additional radiation exposure

For healthcare systems

  • 113% more patients identified compared to traditional screening adherence rates
  • $40K–60K saved per prevented fracture through early intervention and treatment
  • Zero workflow disruption—seamless integration into existing radiology workflows
$2.5B

Annual cost avoidance potential

Estimated annual savings for Medicare with broad implementation and effective follow-through. Every prevented hip fracture saves $40,000–60,000 in acute care, rehabilitation, and long-term complications.

10:1 ROI on prevention vs. treatment costs

Built to deploy, built to scale

The wedge is simple: high-volume CT workflows, minimal friction, and a clear path from risk signal to action.

Commercial model (expected)

Per-site license + per-study usage

Start with a workflow pilot, then scale via a site license with usage-based processing. Integration via PACS or API.

Pricing is finalized with early partners to match volume, integration effort, and clinical outputs.
Go-to-market wedge

Outpatient radiology first

High CT volume, fast decision cycles, and direct incentives to differentiate services. Expand into health systems once the workflow is proven.

  • • Start: abdominal and chest CTs
  • • Deliverable: structured report + risk tier
  • • Outcome: referrals and preventive care coordination
Why we win

Signal + workflow + defensibility

Phantomless calibration makes the measurements comparable across scanners. Multi-domain biomarkers capture more than bone. The product lands where radiologists already work.

Why Quasar BHI is different

BHI is not a DXA replacement—it's an opportunistic, workflow-native risk signal designed to surface fracture risk earlier and at population scale.

Capability
DXA / FRAX
Bone-only CT BMD
BHI (Quasar)
Uses existing CTs (no extra visit)
Scanner-agnostic calibration
varies
Multi-domain biomarkers (bone + muscle + fat)
Workflow integration (PACS / API)
varies
Output: actionable risk tier + report
varies
varies
“Varies” depends on vendor tooling, calibration approach, and how results are operationalized in clinical workflow.

Understanding the science

Three breakthroughs that enable opportunistic screening at scale

Quasar's proprietary calibration technology uses internal tissue references to standardize imaging measurements across scanner manufacturers and protocols. This breakthrough enables true opportunistic screening without external calibration equipment.

Vertebral focus
Vertebral focus
Automated vertebral identification and measurement.
Risk stratification
Risk stratification
Structured output that supports triage and follow-up.
Multi-tissue view
Multi-tissue view
Bone, muscle, and fat features in one index.

What makes this different

Phantomless

Only solution that eliminates external calibration equipment—enabling true opportunistic screening at scale

Multi-domain

First system to combine bone density, muscle quality, and fat distribution into unified fracture risk assessment

Universal

Works across all major CT manufacturers without protocol modifications or workflow changes

26
Patent claims protecting core IP
0.84⁴
AUC fracture prediction vs ~0.71 traditional
<4%⁵
Calibration error vs phantom methods
<60s
Processing time per scan
Note: metrics are representative of internal analysis and will be updated as validation expands.

Validation and regulatory plan

We are executing a staged plan that balances speed, clinical credibility, and deployability.

Retrospective validation
Now

Expand multi-site and multi-scanner evaluation. Lock performance, failure modes, and reporting outputs.

Workflow pilot
Next

Run a real-world integration pilot (PACS/API) to validate turnaround time, usability, and downstream actions.

Regulatory readiness
Planned

Formalize the 510(k) path with predicate mapping, QMS hygiene, and evidence planning.

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Experience meets innovation

Bevan Smith

Bevan Smith

Founder and CEO

Risk and AI-driven strategy background, building clinically grounded products with commercialization discipline.

Clinical Advisor

Clinical Advisor

Consultant Radiologist (UK)

Advises on clinical context, use cases, and validation strategy. Advising in personal capacity (unpaid). No institutional endorsement implied.

ML Engineering

ML Engineering

Technical Team

Execution on POC, productionization, and deployment readiness.

Execution proof

This is not a concept deck. We are building, validating, and preparing for deployment.

Shipped
Done
  • • Provisional patent filed (#63/915,972) with 26 claims
  • • End-to-end pipeline proof-of-concept on real patient CT data
  • • Initial multi-scanner testing and reporting outputs
  • • 510(k) deployment strategy drafted
In progress
Active
  • • Multi-site validation expansion and failure-mode analysis
  • • PACS/API integration hardening for pilot workflows
  • • Output formats: structured report + risk stratification
  • • Partner pipeline for pilot sites
Next up
Near-term
  • • Prospective workflow pilot (turnaround time + adoption)
  • • Evidence plan aligned to 510(k) requirements
  • • Commercial packaging (pricing and deployment playbook)
  • • Scaling plan for additional indications and sites

Join us in preventing the preventable

We are raising pre-seed to complete validation and move through the regulatory pathway.